Reeves, Emer P.: search on Z-Library

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1

Specific Inhibition of the NLRP3 Inflammasome as an Anti-Inflammatory Strategy in Cystic Fibrosis

McElvaney, Oliver J, Zaslona, Zbigniew, Becker-Flegler, Katrin, Palsson-McDermott, Eva M, Boland, Fiona, Gunaratnam, Cedric, Gulbins, Erich, O'Neill, Luke A, Reeves, Emer P, McElvaney, Noel G

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2019

Language:

english

File:

PDF, 1.84 MB

english, 2019

2

Consequences of Abrupt Cessation of Alpha 1 -Antitrypsin Replacement Therapy

McElvaney, Oliver J., Carroll, TomÃ¡s P., Franciosi, Alessandro N., Sweeney, James, Hobbs, Brian D., Kowlessar, Vikita, Gunaratnam, Cedric, Reeves, Emer P., McElvaney, Noel G.

Journal:

New England Journal of Medicine

Year:

2020

Language:

english

File:

PDF, 377 KB

english, 2020

3

The Impact of Smoke Exposure on the Clinical Phenotype of Alpha-1 Antitrypsin Deficiency in Ireland: Exploiting a National Registry to Understand a Rare Disease

O’Brien, M. Emmet, Pennycooke, Kevin, Carroll, Tomás P., Shum, Jonathan, Fee, Laura T., O’Connor, Catherine, Logan, P. Mark, Reeves, Emer P., McElvaney, Noel G.

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2015

Language:

english

File:

PDF, 668 KB

english, 2015

4

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

Clancy, Danielle M., Sullivan, Graeme P., Moran, Hannah B.T., Henry, Conor M., Reeves, Emer P., McElvaney, Noel G., Lavelle, Ed C., Martin, Seamus J.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.54 MB

english, 2018

5

Activation of complement component 3 is associated with airways disease and pulmonary emphysema in alpha-1 antitrypsin deficiency

O'Brien, Michael E, Fee, Laura, Browne, Niall, Carroll, TomÃ¡s P, Meleady, Paula, Henry, Michael, McQuillan, Karen, Murphy, Mark P, Logan, Mark, McCarthy, Cormac, McElvaney, Oliver J, Reeves, Emer P,

Journal:

Year:

2020

File:

PDF, 1.63 MB

2020

6

Increased Outer Arm and Core Fucose Residues on the N -Glycans of Mutated Alpha-1 Antitrypsin Protein from Alpha-1 Antitrypsin Deficient Individuals

McCarthy, Cormac, Saldova, Radka, O’Brien, M. Emmet, Bergin, David A., Carroll, Tomás P., Keenan, Joanne, Meleady, Paula, Henry, Michael, Clynes, Martin, Rudd, Pauline M., Reeves, Emer P., McElvaney,

Journal:

Journal of Proteome Research

Year:

2014

Language:

english

File:

PDF, 2.42 MB

english, 2014

7

Catalase negative Staphylococcus aureus retain virulence in mouse model of chronic granulomatous disease

Carlo G.M Messina, Emer P Reeves, Jürgen Roes, Anthony W Segal

Journal:

Year:

2002

Language:

english

File:

PDF, 123 KB

english, 2002

8

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] D25. CYSTIC FIBROSIS - Constitutive Upregulation Of The TIM-3/Galectin-9 Pathway Augments Neutrophil Inflammation In Infant Cystic Fibrosis Lung Disease

Vega-Carrascal, Isabel, Reeves, Emer P., Niki, Toshiro, Arikawa, Tomohiro, McNally, Paul, O'Neill, Shane, Hirashima, Mitsuomi, McElvaney, Noel G.

Year:

2011

Language:

english

File:

PDF, 18 KB

english, 2011

9

The role of TIM-containing molecules in airway disease and their potential as therapeutic targets

Reeves, Emer, Vega-Carrascal,, McElvaney,

Journal:

Journal of Inflammation Research

Year:

2012

Language:

english

File:

PDF, 1.20 MB

english, 2012

10

Glycosylation Repurposes Alpha-1 Antitrypsin for Resolution of Community-acquired-pneumonia

McCarthy, Cormac, Dunlea, Danielle M, Saldova, Radka, Henry, Michael, Meleady, Paula, McElvaney, Oliver J, Marsh, Brian, Rudd, Pauline M, Reeves, Emer P, McElvaney, Noel G

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2017

Language:

english

File:

PDF, 502 KB

english, 2017

11

Targeting airway inflammation in cystic fibrosis

McElvaney, Oliver J, Wade, Patricia, Murphy, Mark, Reeves, Emer P, McElvaney, Noel G

Journal:

Expert Review of Respiratory Medicine

Year:

2019

File:

PDF, 1.06 MB

2019

12

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 â¢ New Orleans - ()] B33. EOSINOPHILS AND NEUTROPHILS - Impaired Neutrophil Killing Ability And Altered Degranulation Of Antimicrobial Proteins In Cystic Fibrosis

Pohl, Kerstin, Reeves, Emer P., Bergsson, Gudmundur, O'Neill, Shane J., McElvaney, Noel G.

Year:

2010

File:

PDF, 18 KB

2010

13

The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron

Kathrin Reiber, Emer P. Reeves, Claire M. Neville, Robert Winkler, Peter Gebhardt, Kevin Kavanagh, Sean Doyle

Journal:

FEMS Microbiology Letters

Year:

2005

Language:

english

File:

PDF, 348 KB

english, 2005

14

24. Sustained Expression with Partial Correction of Neutrophil Defects 5 Years After Intramuscular rAAV1 Gene Therapy for Alpha-1 Antitrypsin Deficiency

Mueller, Christian, Chulay, Jeffrey D., McElvaney, Noel G., Gernoux, Gwladys, Reeves, Emer P., Rouhani, Farshid N., Humphries, Margaret, Gruntman, Alisha M., Campbell-Thompson, Martha, Wilson, James M

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 407 KB

english, 2016

15

Emerging pharmacotherapies in cystic fibrosis

McElvaney, Oliver J, Gunaratnam, Cedric, McElvaney, Oisin Fiachra, Bagwe, Isha, Reeves, Emer P, McElvaney, Noel G

Journal:

Expert Review of Respiratory Medicine

Year:

2018

File:

PDF, 1.19 MB

2018

16

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 â¢ New Orleans - ()] D58. CYSTIC FIBROSIS: BASIC AND TRANSLATIONAL SCIENCE - The Peripheral Blood Neutrophil In Cystic Fibrosis Has An Altered Membrane Proteome Profile

Hayes, Elaine, Bergin, David A., Vega-Carrascal, Isabel, Keenan, Joanne, Clynes, Martin, Reeves, Emer P., O'Neill, Shane J., McElvaney, Noel G.

Year:

2010

File:

PDF, 19 KB

2010

17

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] B27. BALANCING ACT: NOVEL FUNCTIONS OF THE PROTEASE AND ANTIPROTEASES IN THE LUNG - The Ability Of Alpha-1 Antitrypsin To Inhibit Leukotriene B4 Induced Neutrophil Signalling And The Potential To Reduce Bronchial Inflammation

O'Dwyer, Ciara A., McElvaney, Noel G., Reeves, Emer P.

Year:

2012

File:

PDF, 18 KB

2012

18

Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

Inna S. Afonina, Graham A. Tynan, Susan E. Logue, Sean P. Cullen, Michael Bots, Alexander U. Lüthi, Emer P. Reeves, Noel G. McElvaney, Jan P. Medema, Ed C. Lavelle, Seamus J. Martin

Journal:

Year:

2011

Language:

english

File:

PDF, 2.03 MB

english, 2011

19

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] D54. PNEUMONIA: BENCH TO BEDSIDE - Downregulation Of The 1±, 25 Dihydroxyvitamin-D3 (Vitamin D3) Receptor By Aspergillus Fumigatus Secreted Gliotoxin In Cystic Fibrosis

Coughlan, Catherine A., Reeves, Emer P., Bergsson, Gudmundur, Greene, Catherine M., O'Neill, Shane J., McElvaney, Noel G.

Year:

2010

Language:

english

File:

PDF, 19 KB

english, 2010

20

The Acoustic Features of Inhalation can be Used to Quantify Aerosol Delivery from a Diskus™ Dry Powder Inhaler

Seheult, Jansen N., O’Connell, Peter, Tee, Kee Chun, Bholah, Tariq, Al Bannai, Hasan, Sulaiman, Imran, MacHale, Elaine, D’Arcy, Shona, Holmes, Martin S., Bergin, David, Reeves, Emer, Reilly, Richard B

Journal:

Pharmaceutical Research

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

21

Dysregulated neutrophil function in individuals with alpha-1 antitrypsin deficiency caused by modified membrane cholesterol content.

Bakr Jundi,Michelle White,Noreen Lacey,Noel G McElvaney,Emer Reeves

Journal:

BMC Proceedings

Year:

2015

Language:

english

File:

PDF, 240 KB

english, 2015

22

The design and biological evaluation of a series of 3-hydroxy-3-methylglutaryl coenzyme a (HMG-CoA) reductase inhibitors related to dihydromevinolin.

Elisabeth A. Bone, Emer M. Cunningham, Alan H. Davidson, W.Alan Galloway, Christopher N. Lewis, Elizabeth M. Morrice, Maxwell M. Reeve, Richard S. Todd, Ingrid M. White

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 417 KB

english, 1992

23

GDPR: an impediment to research?

Clarke, Niamh, Vale, Gillian, Reeves, Emer P., Kirwan, Mary, Smith, David, Farrell, Michael, Hurl, Gerard, McElvaney, Noel G.

Journal:

Irish Journal of Medical Science (1922-1925)

Year:

2019

File:

PDF, 499 KB

2019

24

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] B33. EOSINOPHILS AND NEUTROPHILS - Secretory Leukoprotease Inhibitor Regulates Neutrophil Chemotaxis Via Calpain Inhibition

Ryan, Dorothy M., Reeves, Emer P., McElvaney, Noel G., O'Neill, Shane J.

Year:

2010

Language:

english

File:

PDF, 26 KB

english, 2010

25

The Facilitating Effect of Hypertonic Saline on Resolution of Airway Inflammation in Cystic Fibrosis

Reeves, Emer P., McElvaney, Noel G.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2012

Language:

english

File:

PDF, 52 KB

english, 2012

26

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] A107. NEW CONCEPTS IN PROTEASES AND ANTIPROTEASES - Secretory Leukoprotease Inhibitor Prevents Talin Cleavage Via Calpain Inhibition Thereby Influencing Neutrophil Cytoskeletal Rearrangement

Ryan, Dorothy M., Reeves, Emer P., McElvaney, Noel G., O'Neill, Shane

Year:

2011

Language:

english

File:

PDF, 19 KB

english, 2011

27

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] C27. PROTEINASES AND THEIR INHIBITORS IN INFLAMMATION AND INJURY - Alpha-1 Antitrypsin Modulates Neutrophil Activity Through Regulation Of The Calcium Flux

Bergin, David A., Reeves, Emer P., O'Neill, Shane J., McElvaney, Noel G.

Year:

2010

Language:

english

File:

PDF, 19 KB

english, 2010

28

Airway inflammatory markers in individuals with cystic fibrosis and non-cystic fibrosis bronchiectasis

Reeves, Emer, Bergin,, Hurley,, Mehta,, Cox,, Ryan,, O'Neill,, McElvaney,

Journal:

Journal of Inflammation Research

Year:

2013

Language:

english

File:

PDF, 701 KB

english, 2013

29

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 â¢ Denver Colorado - ()] C34. NEUTROPHILS, MAST CELLS, BASOPHILS AND EOSINOPHILS IN LUNG DISEASE - Evidence For Altered Neutrophil Apoptosis In Individuals With Alpha-1 Antitrypsin Deficiency

Hurley, Killian, Reeves, Emer P., Bergin, David A., O'Neill, Shane, McElvaney, Noel G.

Year:

2011

File:

PDF, 18 KB

2011

30

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 â¢ Denver Colorado - ()] C34. NEUTROPHILS, MAST CELLS, BASOPHILS AND EOSINOPHILS IN LUNG DISEASE - Defective Neutrophils Degranulation Induced By TNF-Alpha In Adults With Cystic Fibrosis

Pohl, Kerstin, Reeves, Emer P., O'Neill, Shaun J., McElvaney, Noel G.

Year:

2011

File:

PDF, 19 KB

2011

31

Intracellular Secretory Leukoprotease Inhibitor Modulates Inositol 1,4,5-Triphosphate Generation and Exerts an Anti-Inflammatory Effect on Neutrophils of Individuals with Cystic Fibrosis and Chronic Obstructive Pulmonary Disease

Reeves, Emer P., Banville, Nessa, Ryan, Dorothy M., O’Reilly, Niamh, Bergin, David A., Pohl, Kerstin, Molloy, Kevin, McElvaney, Oliver J., Alsaleh, Khalifah, Aljorfi, Ahmed, Kandalaft, Osama, O'Flynn,

Journal:

BioMed Research International

Year:

2013

Language:

english

File:

PDF, 1.99 MB

english, 2013

32

The Cystic Fibrosis Neutrophil: A Specialized Yet Potentially Defective Cell

Elaine Hayes, Kerstin Pohl, Noel G. McElvaney, Emer P. Reeves

Journal:

Archivum Immunologiae et Therapiae Experimentalis

Year:

2011

Language:

english

File:

PDF, 591 KB

english, 2011

33

Susceptibility of Larvae ofGalleria mellonellato Infection byAspergillus fumigatusis Dependent upon Stage of Conidial Germination

Julie Renwick, Paul Daly, Emer P. Reeves, Kevin Kavanagh

Journal:

Year:

2006

Language:

english

File:

PDF, 320 KB

english, 2006

34

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] B21. NEUTROPHIL STUDIES IN ASTHMA AND COPD - NADPH Oxidase Dysfunction In Alpha-1 Antitrypsin Deficient Neutrophils

Bergin, David A., Reeves, Emer P., O' Neill, Shane J., McElvaney, Noel G.

Year:

2011

Language:

english

File:

PDF, 18 KB

english, 2011

35

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] B33. EOSINOPHILS AND NEUTROPHILS - Secretory Leukoprotease Inhibitor Regulates Neutrophil Chemotaxis Via Calpain Inhibition

Ryan, Dorothy M., Reeves, Emer P., McElvaney, Noel G., O'Neill, Shane J.

Year:

2010

File:

PDF, 26 KB

2010

36

Multiple transformation of Saccharomyces cerevisiae by protoplast fusion

Emer Reeves, Kevin Kavanagh, Peter A. Whittaker

Journal:

FEMS Microbiology Letters

Year:

1992

Language:

english

File:

PDF, 379 KB

english, 1992

37

Endothelial Progenitor Cells in Mothers of Low-Birthweight Infants: A Link between Defective Placental Vascularization and Increased Cardiovascular Risk?

King, Thomas F. J., Bergin, David A., Kent, Etaoin M., Manning, Fiona, Reeves, Emer P., Dicker, Patrick, McElvaney, Noel G., Sreenan, Seamus, Malone, Fergal D., McDermott, John H.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2013

Language:

english

File:

PDF, 438 KB

english, 2013

38

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] A21. FIRST RESPONDERS: MUCOSAL INNATE IMMUNITY - The Essential Role Of TIM-3 In Neutrophil Mediated Gram-Negative Bacterial Killing: An Effect Abrogated Within The Cystic Fibrosis Lung

Reeves, Emer P., Vega-Carrascal, Isabel, McElvaney, Noel G.

Year:

2012

File:

PDF, 17 KB

2012

39

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 â¢ Denver Colorado - ()] D25. CYSTIC FIBROSIS - Elevated Gliotoxin Production By Aspergillus Fumigatus Downregulates Vitamin D Receptor Expression In Cystic Fibrosis Airways

Coughlan, Catherine A., Reeves, Emer P., Bergsson, Gudmundur, Greene, Catherine M., Kavanagh, Kevin, O'Neill, Shaun J., McElvaney, Noel G.

Year:

2011

File:

PDF, 20 KB

2011

40

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 â¢ San Francisco, California - ()] D33. ASTHMA PATHOGENESIS - Autocrine Regulation Of Tumour Necrosis Factor-Alpha Production By Alpha-1 Antitrypsin In Human Neutrophils

Reeves, Emer P., Jameel, Ramia, Bergin, David A., McElvaney, Noel G.

Year:

2012

File:

PDF, 18 KB

2012

41

A novel neutrophil derived inflammatory biomarker of pulmonary exacerbation in cystic fibrosis

Emer P. Reeves, David A. Bergin, Sean Fitzgerald, Elaine Hayes, Joanne Keenan, Michael Henry, Paula Meleady, Isabel Vega-Carrascal, Michelle A. Murray, Teck Boon Low, Cormac McCarthy, Emmet O'Brien, M

Journal:

Journal of Cystic Fibrosis

Year:

2012

Language:

english

File:

PDF, 520 KB

english, 2012

42

Helicobacter pylori Lipopolysaccharide Interacts With TFF1 in a pH-Dependent Manner

Emer P. Reeves, Tehmeena Ali, Paul Leonard, Stephen Hearty, Richard O'Kennedy, Felicity E.B. May, Bruce R. Westley, Christine Josenhans, Melanie Rust, Sebastian Suerbaum, Angeline Smith, Brendan Drumm

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 2.20 MB

english, 2008

43

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] B21. NEUTROPHIL STUDIES IN ASTHMA AND COPD - Alpha-1 Antitrypsin Is A Novel Regulator Of Interleukin-8 Signalling In Neutrophils

Bergin, David A., Reeves, Emer P., O' Neill, Shane J., McElvaney, Noel G.

Year:

2011

Language:

english

File:

PDF, 19 KB

english, 2011

44

Pneumothorax and lung cysts: a family affair

Hawkins, Padraig, Logan, P Mark, Reeves, Emer P, McElvaney, Noel G

Journal:

Lancet (London, England)

Year:

2019

Language:

english

File:

PDF, 354 KB

english, 2019

45

A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus

Emer P. Reeves, Kathrin Reiber, Claire Neville, Olaf Scheibner, Kevin Kavanagh, Sean Doyle

Journal:

Year:

2006

Language:

english

File:

PDF, 581 KB

english, 2006

46

The NADPH Oxidase Components p47phox and p40phox Bind to Moesin through Their PX Domain

Frans B. Wientjes, Emer P. Reeves, Vukic Soskic, Heinz Furthmayr, Anthony W. Segal

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 148 KB

english, 2001

47

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 â¢ Denver Colorado - ()] D25. CYSTIC FIBROSIS - Neutrophil Derived CD16B: Alpha-1 Antitrypsin Complex; A Novel Biomarker Of Inflammation In Cystic Fibrosis

Bergin, David A., Reeves, Emer P., Fitzgerald, Sean, Vega-Carrascal, Isabel, Hayes, Elaine, Keenan, Joanne, Clynes, Martin, Low, Teck B., O' Neill, Shane J., McElvaney, Noel G.

Year:

2011

File:

PDF, 20 KB

2011

48

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] B27. BALANCING ACT: NOVEL FUNCTIONS OF THE PROTEASE AND ANTIPROTEASES IN THE LUNG - Altered Polymorphonuclear Leukocyte Apoptosis In Individuals With Alpha-1 Antitrypsin Deficiency Is Associated With Endoplasmic Reticulum Stress And IL-6 Expression

Hurley, Killian, Bergin, David A., McElvaney, Oliver J., Reeves, Emer P., McElvaney, Noel G.

Year:

2012

Language:

english

File:

PDF, 19 KB

english, 2012

49

Tumor necrosis factor-α driven inflammation in alpha-1 antitrypsin deficiency: a new model of pathogenesis and treatment

Hurley, Killian, Reeves, Emer P., Carroll, Tomás P., McElvaney, Noel G.

Journal:

Expert Review of Respiratory Medicine

Year:

2015

Language:

english

File:

PDF, 1006 KB

english, 2015

50

The human cathelicidin antimicrobial peptide LL-37 promotes the growth of the pulmonary pathogen Aspergillus fumigatus

Sheehan, Gerard, Bergsson, Gudmundur, McElvaney, Noel G., Reeves, Emer P., Kavanagh, Kevin

Journal:

Infection and Immunity

Year:

2018

Language:

english

File:

PDF, 2.36 MB

english, 2018

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